The multi-user version comes in three products: Antidote 11 – French, Antidote 11 – English, and Antidote 11 – Bilingual. Subscribers to the Antidote Maintenance Program (AMP) will find their free upgrade in their Client Portal. Multi-user licenses can be obtained according to a sliding price scale available for five or more workstations.įor all users, the cloud edition, Antidote Web, inherits most of the new features of v2, and Antidote Mobile for iOS benefits from the improvements to the dictionaries and guides. In particular, for the first time, the mobile version features a powerful search by combinable criteria. – Diclofenac and other non‐steroidal anti‐inflammatory drugs (NSAIDs) may limit the passage of gamma hydroxybutyric acid (a narcolepsy medication and illicit party drug commonly known as GHB) to the brain, decreasing the potential for fatal overdose, according to a University at Buffalo study.Antidote 11 for Windows or Mac will automatically prompt you to download the update, and the App Store will do the same thing for Antidote Mobile. The research found that treatment with diclofenac after taking GHB led to decreased concentrations of GHB in the brain and an improved respiration. The study, completed in animal models, was published in Biopharmaceutics & Drug Disposition. Previous studies completed by the UB researchers found that the NSAIDs ibuprofen and ketoprofen also affected the movement of GHB in the body. GHB is approved for a number of clinical uses, including the treatment of narcolepsy, a chronic sleep disorder, and alcoholism. However, GHB prescriptions are limited due to its high potential for abuse as a club and date-rape drug. At high doses, the drug can cause amnesia, drowsiness and depressed breathing. There are currently no approved antidotes for GHB overdose.
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